Daughters et al. (2009) offered proof that the expanded CTG repeat in the ATXN8OS gene is transcribed into an mRNA using an expanded CUG repeat, conferring a toxic get of function that plays a task within the SCA8 phenotype. In brain tissue from humans and mice with SCA8, ATXN8OS mRNA https://acalabrutinib02456.uzblog.net/5-essential-elements-for-rspo1-protein-42558472