Hallucinogens/psychedelics can also be related to novel mechanisms of action in relation to traditional drugs, that happen to be typically based on the monoaminergic imbalance concept. The modulation of cortical five-HT2A receptors and the subsequent increase in glutamatergic tone along with the associated neuroplasticity are novel mechanisms of action.seven,forty one,60 https://nimmansocial.com/story7475837/the-definitive-guide-to-lsd-history-and-cultural-impact