-dihydroxyphenyl rings of procyanidin C1 have been located in the composition mimicking K2E2·Pi point out. This interaction causes the ion pathway (which is formed by residues which includes one of the interacting arginines, R979) to become inaccessible with the extracellular side76. This binding mode may thus sterically impede ion Trade. https://onc21244321.idblogmaker.com/29088461/getting-my-cy5-5-to-work