The main circulating metabolite of ketamine (norketamine) demonstrated exercise at the identical receptor with considerably less affinity. Norketamine is about 1/3 as active as ketamine in lessening halothane necessities (MAC) of the rat. There won't be any data on pregnancy exposures in primates comparable to durations before the 3rd trimester https://ketalinic.com/ketamine-r-isomer-s-isomer/