further more illuminating issues, function and therapeutic efficacy of MSCs are extremely regulated with the surrounding market/microenvironment (Zhu et al., 2016; Mehrbani Azar et al., 2018; Tejero et al., 2019; https://dailybookmarkhit.com/story18398043/how-mesenchymal-stem-cells-differentiation-can-save-you-time-stress-and-money