Activation of neuronal CB1 receptors brings about inhibition of adenylyl cyclase and lowered neurotransmitter release by means of blockade of voltage-operated calcium channels.[forty six,65,125] The activation of these signaling pathways by CB1 receptors along with the substantial amounts of these receptors on presynaptic terminals signifies that endocannabinoid stimulation of CB1 https://emilianovbhmk.bloguetechno.com/how-cannabis-flower-can-save-you-time-stress-and-money-67997138