Abstract ZIF-8 may experience ion-responsive degradation in ionic solutions. which will change its initial architecture and restrict its direct biological use. Herein. we report an abnormal phenomenon in which ZIF-8 induces large hydroxyapatite-like crystals when soaked directly in simulated body fluid. https://www.nacrack.com/quick-buy-Whelen-Arges-Remote-Spotlight-amazing-deal/