Butabarbital raises toxicity of methoxyflurane by raising metabolism. Contraindicated. Greater metabolism of methoxyflurane to nephrotoxic compounds. butabarbital will lower the extent or result of midazolam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. butabarbital will reduce the extent or result of ramelteon by impacting hepatic/intestinal enzyme ... https://moseleyc320waz9.techionblog.com/profile