Butabarbital will increase toxicity of methoxyflurane by escalating metabolism. Contraindicated. Greater metabolism of methoxyflurane to nephrotoxic compounds. butabarbital will reduce the extent or effect of levamlodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. butabarbital will reduce the extent or effect of alprazolam by impacting hepatic/intestinal enzyme CYP3A4 ... https://peterv357rtv1.livebloggs.com/profile